Useful access to enantiomerically pure protected inositols from carbohydrates: the aldohexos-5-uloses route

• Felicia D’Andrea,
• Giorgio Catelani,
• Lorenzo Guazzelli and
• Venerando Pistarà

Beilstein J. Org. Chem. 2016, 12, 2343–2350, doi:10.3762/bjoc.12.227

• ; intramolecular aldol condensation; stereoselective hydride reduction; Introduction Inositols are a family of biologically relevant compounds [1][2] constituted by nine stereoisomeric hexahydroxycyclohexanes (Figure 1): five have been found in nature (myo, scyllo, D-chiro, L-chiro, and neo), while the remaining